Microglia are the resident macrophages in the central nervous system (CNS). One of their most important characteristics is their ability to phagocytose, which plays a pivotal role in maintaining brain homeostasis and responding to neurodegenerative diseases. In vitro microglial phagocytosis assays assist in understanding how microglia maintain tissue homeostasis in healthy and disease states.
Our optimized physiological culture method accurately reproduces the characteristics and morphology of microglia in vivo. Additionally, our laboratory is equipped with a live cell imaging device designed to effectively capture the cellular changes that occur throughout the life cycle of microglia, enabling long-term measurements and real-time cell visualization.