Introduction to N7 -methylguanosine (m7G) Post-transcriptional regulation of mRNA fate is aided by mRNA modifications. Although N6-methyladenosine (m6A) has been shown to influence mRNA metabolism in mammals, it has also been hypothesized that positively charged base modifications, such as N1 -N1-N1-methyladenosine (m1A), could tune RNA secondary structures of protein-RNA interactions within...